Development and validation of an open access SNP array for 2 Nile Tilapia (Oreochromis Niloticus)

cg.contribution.worldfishauthorTrinh, T.Q.en_US
cg.contribution.worldfishauthorMahmuddin, M.en_US
cg.contribution.worldfishauthorBenzie, J.en_US
cg.contributor.affiliationWorldFishen_US
cg.contributor.affiliationUniversity of Edinburgh, College of Medicine & Veterinary Medicine, The Roslin Instituteen_US
cg.contributor.crpFishen_US
cg.contributor.funderCGIAR System Organizationen_US
cg.coverage.regionGlobalen_US
cg.creator.idMahirah Mahmuddin: 0000-0002-4907-7784en_US
cg.creator.idJohn Benzie: 0000-0001-9599-8683en_US
cg.description.themeAquacultureen_US
cg.identifier.ISIindexedISI indexeden_US
cg.identifier.statusOpen accessen_US
cg.subject.agrovocaquacultureen_US
cg.subject.agrovocnile tilapiaen_US
dc.creatorPenaloza, C.en_US
dc.creatorRobledo, D.en_US
dc.creatorBarria, A.en_US
dc.creatorTrinh, T.Q.en_US
dc.creatorMahmuddin, M.en_US
dc.creatorWiener, P.en_US
dc.creatorBenzie, J.en_US
dc.creatorHouston, R.en_US
dc.date.accessioned2020-06-29T07:05:32Z
dc.date.available2020-06-29T07:05:32Z
dc.date.issued2020en_US
dc.description.abstractTilapia are amongst the most important farmed fish species worldwide, and are fundamental for the food security of many developing countries. Several genetically improved Nile tilapia (Oreochromis niloticus) strains exist, such as the iconic Genetically Improved Farmed Tilapia (GIFT), and breeding programmes typically follow classical pedigree-based selection. The use of genome-wide single-nucleotide polymorphism (SNP) data can enable an understanding of the genetic architecture of economically important traits and the acceleration of genetic gain via genomic selection. Due to the global importance and diversity of Nile tilapia, an open access SNP array with known utility across multiple tilapia strains would be beneficial for aquaculture research and production. In the current study, a ~65K SNP array was designed based on SNPs discovered from whole-genome sequence data from a GIFT breeding nucleus population and the overlap with SNP datasets from several other farmed and wild Nile tilapia strains. The SNP array was applied to clearly distinguish between different tilapia populations across Asia and Africa, with at least ~30,000 SNPs segregating in each of the diverse population samples tested. It is anticipated that this SNP array will be an enabling tool for population genetics and tilapia breeding research, facilitating consistency and comparison of results across studies.en_US
dc.identifier.citationPeñaloza, C. (2020). Development and validation of an open access SNP array for 2 Nile Tilapia (Oreochromis Niloticus). G3: Genes Genomes Genetics, online first 12 June.en_US
dc.identifier.doihttps://dx.doi.org/10.1534/g3.120.401343en_US
dc.identifier.issn2160-1836en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12348/4202
dc.languageenen_US
dc.publisherGenetics Society of Americaen_US
dc.rightsCC-BY-NC-4.0en_US
dc.sourceG3: Genes|Genomes|Genetics;(2020)en_US
dc.subjectgiften_US
dc.subjectsnp arrayen_US
dc.subjectabbassaen_US
dc.subjectFishen_US
dc.titleDevelopment and validation of an open access SNP array for 2 Nile Tilapia (Oreochromis Niloticus)en_US
dc.typeJournal Articleen_US

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